What are benefits of glutathione?
Glutathione, a potent antioxidant, is present in every cell of the body and is composed of three amino acids. These amino acids form various combinations to create all the body’s proteins. Glutathione is unique in that the liver can produce it, which is not the case for most other antioxidants.
The functions of glutathione are diverse and crucial, including:
- Synthesizing DNA, the fundamental building blocks of proteins and cells.
- Supporting immune system function.
- Contributing to the formation of sperm cells.
- Neutralizing some free radicals.
- Aiding the function of certain enzymes.
- Regenerating vitamins C and E.
- Assisting in mercury transportation out of the brain.
- Facilitating the liver and gallbladder in processing fats.
- Playing a role in the natural process of cell death, known as apoptosis.
Research has identified a connection between low glutathione levels and certain diseases. It’s possible to raise glutathione levels through oral or intravenous (IV) supplementation. Another approach is to take supplements that stimulate the body’s natural production of glutathione, such as milk thistle, N-acetyl cysteine, and superoxide dismutase.
Additionally, reducing toxin exposure and increasing the consumption of healthful foods are effective natural methods to boost glutathione levels in the body.
1) Antioxidant activity
Free radicals are known to play a role in the aging process and the development of some diseases. Antioxidants counter these free radicals, helping to shield the body from their harmful effects. Glutathione stands out as an exceptionally potent antioxidant, largely due to its high concentration in every cell of the body. This widespread presence allows it to effectively combat oxidative stress and protect cellular integrity, contributing to overall health and wellness.
2) Preventing cancer progression
Some research sources indicate that glutathione may play a role in inhibiting the progression of cancer. However, this research also suggests that glutathione could potentially make tumors less responsive to chemotherapy, a standard treatment for cancer. This dual nature of glutathione’s impact on cancer highlights the complexity of its role and underscores the need for further research to fully understand its effects on cancer development and treatment. This ongoing research is crucial for determining how glutathione can be effectively and safely utilized in cancer therapy.
3) Reducing cell damage in liver disease
Hepatitis, alcohol abuse, and fatty liver disease are all conditions that cause damage to the liver’s cells. A small clinical trial conducted in 2017 suggests that glutathione may be beneficial in treating nonalcoholic fatty liver disease. This potential therapeutic effect is attributed to glutathione’s antioxidant properties and its ability to detoxify the body.
4). Improving insulin sensitivity
Insulin resistance is a condition that can lead to the development of type 2 diabetes. It occurs when the body’s response to insulin, the hormone responsible for moving glucose from the blood into cells for energy, becomes less effective.
A small study conducted in 2018 found that individuals with insulin resistance typically have lower levels of glutathione, especially if they have developed complications related to diabetes, such as neuropathy (nerve damage) or retinopathy (eye damage). A similar conclusion was reached in a 2013 study. These findings suggest a potential link between glutathione levels and the severity or progression of conditions related to insulin resistance.
5). Reducing symptoms of Parkinson’s disease
According to certain research, there is evidence suggesting that maintaining adequate glutathione levels might be beneficial in managing the symptoms of Parkinson’s disease. These findings particularly point towards the potential of injected glutathione as a therapeutic option. However, there is limited evidence regarding the effectiveness of oral glutathione supplementation for Parkinson’s disease. Consequently, further research is required to substantiate the use of glutathione, whether through injections or oral supplements, as a viable treatment for Parkinson’s disease symptoms. This additional research is crucial to establish a clearer understanding of glutathione’s role and efficacy in Parkinson’s disease management.
6). Reducing ulcerative colitis damage
Ulcerative colitis, like other inflammatory diseases, is associated with oxidative damage and stress. A 2003 animal study suggests that glutathione supplementation may alleviate some of the damage inflicted on the colon in rats.Â
7). Treating autism spectrum disorders
Some evidence suggests that children with autism have lower levels of glutathione compared to neurotypical children, or those without autism. A study conducted in 2011 found that oral glutathione supplements or injections might have the potential to mitigate some effects of autism.
Takeaway
Glutathione is a potent antioxidant naturally produced and utilized by the body. Researchers have linked low levels of glutathione with various medical conditions. Although supplementation may be beneficial for some individuals, it’s important to note that these supplements may not be safe for everyone. They could potentially interact with other medications a person is taking.
Therefore, it is essential to consult with a doctor before starting glutathione supplementation. A healthcare professional can help determine whether glutathione supplementation is safe and likely to be effective for your specific health needs and conditions, considering any other medications or treatments you may be undergoing.
